In the face of rapid digital transformation, organizations are confronted with the dual challenge of leveraging technological advancements while adhering to principles of social responsibility. This paper explores the critical roles of leadership and human resource management in navigating this complex landscape, aiming to bridge the gap between digital innovation and ethical, societal considerations. Through a comprehensive literature review and insights from focus groups, we delve into the strategies, challenges, and opportunities inherent in fostering responsible innovation. Our findings highlight the importance of visionary leadership and strategic human resource management practices that prioritize continuous learning, diversity, and inclusivity. Theoretically, this study contributes to the discourse on responsible innovation, emphasizing the human-centric aspects of digital transformation. Practically, it offers actionable insights for leaders and HR professionals seeking to embed social responsibility into their organizational strategy and culture. Future research directions are suggested to further understand the effective leadership qualities and HR practices across different contexts. This paper underscores the imperative of a human-centric approach to digital transformation, advocating for a balance between technological advancement and social responsibility.