The paper aims to pointing out the hybridization paths that organizations could embrace to try combine profit, economic sustainability and to reach – at the same time – their social mission. The work intends to contribute to organizational and strategic management literature by focusing on the emergence of hybrid organizations through the analysis of a project of urban regeneration. Through a case study analysis, our research deals with organizations that through a project of re-functionalization boost environmental and economic development, creating a community of cultural and creative actors. Our findings highlight how hybrid organizations can promote social activities, job inclusion and training emphasizing the principles of cooperation, sustainability, and social entrepreneurship.