Purpose – The task of reverse logistics is to retrieve (diverse kind of) value from so-called reverse flows such as returned products, products scraps, production waste, packaging, etc. To assure the effectiveness of reverse logistics the companies often need to apply tailor-made solutions; this requires innovativeness from logistics specialists as well as from executive management. The paper explores the links between perceived effectiveness of reverse logistics and selected variables – factors – that are related to managerial approaches (to reverse logistics and to corporate management in general). The investigated factors are the level of formal planning, the intensity of coordination with 1-tier supply chain members, knowledge management, and quality management (defined as one aspect of organizational culture). In the second step, we investigate the link between RL- effectiveness and one aspect of organizational culture – the managerial approach to programs. Design/methodology/approach – The causal and correlation models are proposed and tested on data that were collected through interviews with representatives of 149 Czech companies. The majority of presented findings are based on subjective statements of informants due to the fact that many questions asked for the data that companies don’t measure, collect and reprocess. The items utilized in the paper were reprocessed by means of bi- and multivariate statistics. Originality/value – The originality stems from the fact that the paper tests empirically a structural model of factors for effective reverse logistics. Second, it test link between the reverse logistics effectiveness and organizational culture. The knowledge management, the extent of planning and external integration/coordination with both suppliers and customers can be considered to be factors of effective reverse logistics. The factor of external coordination speaks in favour of supply chain management in reverse flows: higher value from reverse flows can be recovered if the reverse logistics activities are coordinated on supply chain level, not on the company level solely. Next, the empirical study confirms that effort in application of knowledge management brings also benefits for companies in the field of reverse logistics. Thirdly, the effective reverse logistics is related to an organizational culture that put emphasis on formalization (work standardization) as well as TQM principles.