There is an increasing evidence that highlights the technical and managerial innovations are necessary for firm survival. However, there is limited focus on the relationship between employee well-being and resilience on innovations in an organisational context. The purpose of this conceptual paper is to map the relationships between concepts of employee well-being, resilience in the context of achieving workplace innovation outcomes. This conceptual paper reviews the literature on three sets of theoretical lenses: workplace innovations, organisational ambidexterity and HRM practices in supporting innovation and with an additional focus on individual level influences of employee well-being and resilience and its relationship on innovation. This paper is to the best of our knowledge is the first conceptual review that provides a multi-level review of the three disparate yet related sets of literatures and its impact on organisational innovation outcomes. In doing so, this study also fills the gap on the micro-level foundations of individual employee well-being and resilience and its relationship with innovation.