The paper presents the results of the differentiation of KM tools depending on the certain knowledge domain. This research was done as part of INNOVARRA project (Innovations in Company Knowledge Management: Typology, Methodology and Recommendations) which aims to identify methods and tools of knowledge management (KM) for specific company knowledge domains, which also affect the performance in Russian companies. Identification and systematization of KM methods and tools was initially done by literature review. Then the results were discussed and reviewed through the interviews with KM experts during two international practice-oriented conferences. Specifics of KM for several domains were also studied within INNOVARRA project using surveys, case study and interviews. New methods for the selected domains were developed with the help of design science research methodology. This research puts in evidence on the issue of KM methods suitable for the particular knowledge domain and type. KM tools are differentiated in the study as “universal” and domain-specific ones with a special focus on a number of domains: customer knowledge, operations management knowledge, and strategic management knowledge. Described in the study interrelations between knowledge domains, KM methods and tools may help knowledge managers to select а proper method/tool. Such a selection can be applicable either for the whole company or for certain functional areas.