Purpose – The raison d’etre of entrepreneurship is to create value which ordinarily results from forward activities and processes. The goal is to create value that would provide long-term existence of business, support on keep-going and maintain the running of operations and contribute to the development and growth. All those terms can be replaced by modern concept serving as synonym, i. e. to sustain. Competence or ability to sustain in business stands for still more frequently used term of sustainability. From rather narrow original understanding of term meaning focusing attention and effort of managers on financial or economic aspects of entrepreneurial activities prevalently, its contemporary comprehension has been broadened to other horizons. Even though they can be named differently, it is possible to include them in the so called Tripple Bottom Line where except the economic part of the needed entrepreneurial thinking and behaviour also two other parts belong, namely social and environmental matters. However, firms have to engage also to more or less backward operations. Such operations can be initiated either by external stakeholders (in most cases by customers) or by internal stakeholders (employees and/or managers on the grounds of several reasons), can be solved and managed within the boundaries of individual firm, but usually are under way among the members of some supply chains or networks within the reverse logistics or reverse supply chain processes. Their occurrence and dealing with can have significant impact on all three parts (or pillars) of Triple Bottom Line aspects of business itself and the society, both negative and positive. Sustainability orientation of entrepreneurs and managers is the core to make use of these backward (or reverse) flows to be sustainable in business and to be able to create sustainable value and competitive advantage. The purpose of this paper is to gain more knowledge of the complex area of sustainable oriented entrepreneurship from the point of view of reverse logistics management. Design/methodology/approach – A theoretical framework based on literature review was developed to determine variables of sustainability orientation of entrepreneurs and reverse logistics practices related to sustainable entrepreneurship. Statistical analysis (multiple regression) of empirical data gathered by means of questionnaire was applied to test the relationship among employed independent and dependent variables. Originality/value – To our best knowledge this paper is among just few existing, which investigate a combination of several Triple Bottom Line conceptualization of sustainable entrepreneurship and sustainability orientation of reverse logistics management. The paper and presented findings can serve as a spring board for future research on the topic. Practical implications – The outcomes of the analysis stress the need for understanding of reverse flows management impact and relation to sustainability performance criteria of entrepreneurial activities.