Due to the complexity and variability of society, innovation is necessary to introduce changes that support social growth. At the same time, to support innovation it is necessary to formalize new concepts and approaches such as ecosystems (Bifulco et al., 2016). The research aims to investigate how the participation of people with disabilities in cultural ecosystems can give rise to innovative forms of governance that protect the right to cultural enjoyment for people with disabilities and which at the same time represent an innovation in the field of cultural governance. To analyze this phenomenon the authors chose to use the qualitative methodology of the single case study (Creswell, 2018) represented by the “More than Words” project. The results of the research highlight an effective increase in social and cultural value due to the participation of people with disabilities in the cultural ecosystem created with the aim of audience development of the target group of people with disabilities.