The importance of right speed, effectiveness, efficiency and learning in Multi Business Model Innovation (MBMI) is vital to meet today’s Volatile, Uncertainty, Complex and Ambiguous (VUCA) challenges to survive as a business in Business Model Ecosystems (BMES). VUCA events coursed by external and internal sources make some of the big challenges in 2023 to businesses. How can businesses under these “VUCA World conditions” do high quality MBMI and knowledge management? How is it possible to stay positive and influence MBMI participants and teams in these processes to be and stay optimistic, create and capture knowledge – to increase their MBMI output, performance, competence, capability and courageous appetite on doing MBMI? This paper investigates the impact between a positive mindset and knowledge innovation MBMI processes in BMES´s influenced by VUCA Events. The impact of positivity is studied in 3 MBMI cases as competences to endure challenging MBMI processes influenced by different kinds of VUCA Events. From the cases a transfer of knowledge from tacit into explicit and internalized knowledge is outlined. The involved persons demonstrate preference for socialization processes, learning in pairs and groups as learning and creating by doing. They are very easy to internalize what they have learned in the VUCA. This corresponds to the hypothesis that a positive mindset is a predictor for success in MBMI. The research is conducted in the view of Knowledge Management, MBMI and psychological theory – particularly the concept of positivity as fundamental for better creating and increasing learning and knowledge creation – the vital “raw material” in all MBMI and especially in a VUCA world. Our research shows that individuals embedded in networks and teams and with a general mood of positivity strengthens the MBMI processes. The paper finds that knowledge about the impact of positivity is very useful in MBMI processes influenced by VUCA.