In recent years, the discussion around virtual influencers has been growing. These virtual personalities have a huge following among young people, with an engagement rate three times higher than that of YouTubers. This has made people realize the business opportunities in this industry. To explore how influencer attributes and perceived characterizations affect consumers’ purchase intention, this study uses the S-O-R theoretical framework proposed by Mehrabian and Russell in 1974. The study focuses on three influencer attributes: attitude homophily, physical attractiveness, and social attractiveness, and three perceived characterizations: trustworthiness, parasocial interaction, and brand equity. Perceived characterizations are regarded as a mediator in this study. The research sample consists of 479 people who were sampled from VTubers research groups on social media. The study uses structural equation modeling (SEM) to test the proposed model. The results show that influencer attributes have a significant and positive effect on perceived characterizations. Perceived characterizations, in turn, have a significant and positive effect on consumers’ purchase intention. Additionally, perceived characterizations have a significant mediation effect. This research provides valuable insights for VTubers marketers. By understanding the influence of attributes and characterizations, marketers can develop more effective strategies for promoting their products and services through virtual influencers. In conclusion, virtual influencers have a significant impact on consumers’ purchase intention, and this study provides important insights into how influencer attributes and perceived characterizations affect consumer behavior. By understanding these factors, VTubers marketers can improve their marketing strategies and better leverage the power of virtual influencers.