The study aims to investigate the digital transformation processes within the agri-food sector and their influence on business model innovation (BMI) as a pathway toward sustainability. Specifically, it analyses how agri-food companies are exploiting the potential of digital technologies (DTs) to reshape their value creation processes, enhance competitiveness, and address environmental and economic challenges. In order to exploit DTs and integrate them into business operations, it is essential to innovate the companies’ business model by rethinking traditional operational and strategic logics. This underscores the necessity of both the adoption of new technologies and the transformation of the business model. Despite the multiple opportunities offered by DTs, their introduction in agri-food companies presents significant obstacles due mainly to a lack of knowledge, limited digital skills or to the high costs associated with their implementation. Addressing these barriers, requires a growing emphasis on knowledge co-creation-oriented approaches, that integrate diverse disciplines and sectors. In order to pursue this objective, the study adopts a theoretical approach, based on an analysis of the existing literature on DTs and their role in fostering BMI and sustainability, and boundary management within the agri-food sector. The research focuses on the role of company boundaries as collaborative spaces that can facilitate the adoption of DTs and promote co-creation dynamics. The findings of the research lead to the development of a theoretical framework aimed at guiding agri-food companies in their transition toward more innovative and sustainable business models. This study offers theoretical contributions to support companies in leveraging DTs for sustainable development.