This paper aims to propose alternatives of knowledge management (KM) implementation in SME’s in the state of Santa Catarina. In Brazil and many other countries, most businesses are small and medium-sized, and have a key role in economic growth, employment generation and wealth creation (Lin, 2014, Durst, Edvardsson, 2012). The implementation of KM initiatives in SME’s is particularly relevant (Dotsika, Patrick, 2013), because with intense global competition, and the more large companies deploy KM strategies, the greater the demand for integration of knowledge on the part SMEs. (Supyuenyong, Islam, Kulkarni, 2009). Unfortunately Brazilian companies grow slowly compared to the global market, especially when it comes to offering differentiated and competitive products (Portal CNI, 2014). They need solutions that can help them improve this situation. The question that guides this research is: how best KM deployment alternative for SMEs in Santa Catarina? After the investigation of existing KM models or frameworks aimed at SMEs, it was selected a framework considered compatible with the characteristics of Brazilian SMEs, more specifically, tree manufacture enterprises in the State of Santa Catarina. We propose in this study a multiple case study, descriptive and exploratory. The European Guide to Good Practice in Knowledge Management, who presented the implementation of a framework in SME was chosen. We identified with the instrument suggested by the framework, that the storage as a critical activity of knowledge in the three SME’s studied. A new data collection was carried out to obtain more information about KM storage activity in each of the companies studied. Then, KM instruments were researched on storage activity. Finally two instruments were selected for preparation of implementation plans. This methodology puts in evidence the need for research that help Brazilian SMEs, specifically those located in Santa Catarina, to improve their knowledge management processes, which will keep them operative and stronger in the market, impacting society in social and economic terms. The main implications of the research arising from the study to show the application of parts of a knowledge management framework chosen, in order to identify KM alternatives for SME’s Santa Catarina that little or no work the issue to improve its internal performance and marketplace.