Customers and their requirements are increasingly influencing product development and production processes and at the same time products are becoming more and more individualized. Thus, individualization is no longer restricted to the final products; it increasingly influences all process of companies. New strategies and methods for an effective and flexible management of the production system are needed that include a certain agile approach to personnel planning and deployment. Existing approaches do not meet these requirements of dynamic production environments. We propose an approach which allows connecting flexible process networks with a model-based dynamic competence management. The flexibility of the process network, used for all enterprise processes in the company, is created by a modular framework for the process description. Flexibility in this case means, that the structures can be easily changed for every customer order. This approach offers the possibility to describe required skills in relation to processes and to assign them to employees, so that the planning of the needed staff does not remain on fixed role concepts and offers an increased degree of freedom in planning. Competence management largely relies on competence profiles of individual employees. These profiles are matched to specific positions, thus the flexibility to engage personnel in cross-position tasks is impeded. A decoupling from individuals and the compilation of competence-based reference models is a significant step towards agile human resource management in flexible production systems. The organizational and production process automation is progressed in terms of the deployment of personnel controlled by the process itself. Furthermore, the human resource development is enhanced via process controlled coaching and mentoring, where idle capacity of personnel is assigned to tasks for transferring implicit knowledge additionally. The combination of flexible process networks and dynamic human resource management leads to increases in productivity, effectiveness and implies new approaches e.g. under the constraints of Industry 4.0. Especially in combination with models of flexible working and the resulting new forms of employment the employees are actively involved in the future by bringing in all of their skills which leads to an increase of their individual responsibility. Furthermore, this approach could be a solution to counter the demographic change, as the required competences for the considered processes are referenced to the respective personnel along with demographic data.