Integration of advanced 5G technologies in future business models will enable businesses to offer new disruptive, virtual and persuasive business models (BMs) that business community and society have never seen before. With this comes new and disruptive ways to download, see, sense, generate, capture, deliver, receive and share knowledge between BM´s, humans and machines. Advanced, changed and new approaches to knowledge sharing in multi Business Model Innovation (MBMI) will hereby be a reality. These approaches to knowledge and knowledge sharing will play important role in future business model ecosystems (BMES) “life” and “sustainability”. Future Knowledge based Business Model Ecosystem (KBMES) will enable creation of of BM´s operating within real time, anywhere, with anybody and with anything. They will be operating proactive and not just reactive – and they will be formed persuasive to knowledge creation, capturing, delivery, receiving and consumption. The paper investigates some of our first investigations on these 5G knowledge based business models and systems. The paper examine how advanced 5G MBMI technologies will impact knowledge sharing and knowledge generation in multi business model innovation (MBMI) in the future. The paper present a conceptual framework on how to facilitate knowledge sharing in MBMI with advanced 5G technologies for the purpose of “creating, capturing and delivering BM´s to KBMES with high quality, effectiveness and efficiency in a time where the “life” of BM´s continuously diminishes and demands change in realtime.