This research paper focuses on examining the impact of cloud computing on knowledge processes and innovation in logistics within Industry 4.0. Using a quantitative literature review methodology, the study explores existing literature from 2019 to 2024. The results reveal fluctuations in cloud computing adoption in logistics, with notable growth in recent years. Cloud computing applications are widespread, particularly in supply chain management, transportation, and warehousing. Findings show that cloud computing significantly impacts knowledge processes and innovation in logistics. It enables real-time data processing, enhances decision-making, and supports collaboration across the supply chain. Moreover, cloud technologies foster Smart Logistics, leveraging IoT, AI, and automation for efficiency and sustainability. Despite these benefits, limitations include the reliance on literature review methodology and the rapidly evolving nature of technology. Future research should employ empirical methods to capture practical insights and address emerging challenges, such as data security and sustainability. In conclusion, cloud computing offers substantial benefits for logistics within Industry 4.0, driving efficiency, competitiveness, and innovation. However, addressing challenges and staying abreast of technological advancements are crucial for maximizing its potential in logistics operations. This study contributes to a deeper understanding of the transformative role of cloud computing in logistics and sets the stage for further research in this dynamic field.