Research in the areas of management and strategy commonly considers the issue of networks as a really broad issue in the organizational phenomenon but little addressed by its complexity (Moliterno & Mahony, 2011). However, recent studies have invited to different methodological approaches to distinguish different types of variables among networks issues (Chen, Chang, & Chang, 2015; Ofem, 2015; Oyedokun Akintunde, Adele Ademola, Ogunkunle Oluwatobi, & Adegbile Aderibigbe, 2016; Peltier & Naidu, 2012; Toledano, Urbano, & Bernadich, 2010). Despite the development of these studies, especially in Anglo-Saxon contexts, in Latin American countries have been less addressed, despite being described as an important area in the research agenda for management (Ferreira, Reis, & Miranda, 2015). For some authors, the absence of an integrated theory of networks in management has led them to design theoretical proposals, such as Moliterno & Mahony (2011) who suggested the multilevel capacity in organization’s networks, explained by different actors and interactions between them. In this paper we focus in to measure and analyze the relationship between Collaborative Managers Networks (CMN) and Performance of Small and Medium-sized Enterprises (SMEs) in an emergent economy like Mexico, to provide recommendations to managers to integrate collaboration with different actors in management practices into their business strategies. The designed theoretical model was contrasted through a system of partial least squares (PLS-SEM) of structural equations modeling, using the SmartPLS® software (Ringle, Wende, & Becker, 2015) obtaining information from 170 SMEs operating in the Bajio Region (México) in the leather-footwear sector. The results provide evidence that companies with CMN have a positive effect on its firm performance. However, the majority of networks are oriented just on building links with business actors. Financial and political actors are less involved in managerial practices of collaboration. These findings have strategic implications for the entrepreneurs, mainly in getting advantage in new strategies of collaboration among new actors. This paper provides evidence of four main CMN insights. Firstly, derived from literature research, a CMN conceptual approach. Secondly, the research findings support understanding on the relationship between CMN and Mexican SMEs Performance and propose a multiple dimension CMN model using PLS-SEM as statistical tool. Thirdly, a Spanish adapted test of CMN that use measuring scales in a Latin-American country. Finally, this research attempts to recommend innovative networking strategies in managerial practices and entrepreneurial dynamics on SME companies.