Knowledge generation in healthcare has accelerated in the past years due to the abundance of data captured and information produced. The main reason being the evolvement of the health system into a connected care model which is supported by the advances in medical and other technologies. This accelerated innovation brought more risks related to managing knowledge assets and flows. Extant research suggests that the fields of knowledge risks (KR) and knowledge risk management (KRM) in health has not received adequate attention yet. This paper aims at developing a KRM framework for healthcare organizations. This framework profiles relevant KR found in healthcare and proposes control measures to mitigate them. It also maps responsible units and personnel for implementing the proposed control measures. The development of the framework builds on recent work by the authors, who developed a knowledge risks (KR) taxonomy for healthcare organizations. This paper provides a basic KRM framework within the healthcare context, which is the first of its kind. This paper hopes to further promote discourse in KRM literature and raise the awareness and understanding of KRM practices among healthcare researchers and practitioners. Additionally, the proposed framework can have practical implications when applied in healthcare organizations for improving the overall quality of care, efficiency savings and promoting sustainability of health organizations.